The Hypertension Cardiovascular Outcome Prevention and Evidence in Asia (HOPE Asia) Network
Asia BP@Home study
Primary results
Home blood pressure control status in 2017‐2018 for hypertension specialist centers in Asia: Results of the Asia BP@Home study
Kario K et al. and HOPE Asia Network.
J Clin Hypertens (Greenwich). 2018 Dec;20(12):1686-1695.
PMID 30444315.
The Asia BP@Home study was a prospective, multicenter, non‐interventional trial designed to collect home blood pressure (BP) data from outpatients living in Asian countries and regions.
Medicated hypertensive patients (>=20 years old) were enrolled from 15 Asian specialist centers in 11 countries/regions (China, India, Indonesia, Japan, Korea, Malaysia, Pakistan, Philippines, Singapore, Taiwan, and Thailand) between April 2017 and March 2018.
Patients measured their blood pressure with the same validated home BP monitoring device (Omron HEM‐7130‐AP or HEM‐7131‐E; Omron Healthcare, Kyoto, Japan) at home for at least 7 days during a 15 day HBPM period.
Results:
A total of 1467 patients were recruited and data from 1443 patients were included in the analysis. Well‐controlled morning home systolic BP (<135 mm Hg) was documented in 68.2% of patients, and 55.1% had well‐controlled clinic systolic BP (<140 mmHg). Even using the 2017 AHA/ACC threshold of 130 mm Hg, 53.6% of patients were well controlled for morning home SBP and 32.3% were well controlled for clinic systolic BP <130 mm Hg.
Conclusion:
The Asia BP@Home study demonstrated that home BP is relatively well controlled at hypertension specialist centers in Asia. However, almost half of patients remain uncontrolled for morning BP according to 2017 AHA/ACC guidelines, with significant country/regional differences.
Sub studies
Comparison of day-to-day blood pressure variability in hypertensive patients with type 2 diabetes mellitus to those without diabetes
Chia YC, et al.
J Clin Hypertens (Greenwich). 2020 Mar;22(3):407-414.
In this sub- study, 25.1% (362) of the total patients (1443) had diabetes.
The mean morning home systolic blood pressuer (BP) was significantly higher in hypertensive with diabetes compared to those without (132.3 ± 15 mm Hg vs 129.7 ± 14.4 mm Hg, P = .005, respectively), while there was no difference in the mean clinic systolic BP between the two groups (139.9 ± 17.5 vs 138.4 ± 18.6, P = .188, respectively). Masked morning uncontrolled hypertension (clinic systolic BP of < 140 mm Hg together with morning home systolic BP of >= 135 mm Hg) was also greater in those with diabetes (12.8% vs 8.4%, P = .02).
There was no statistically significant difference in BP variability of the morning, evening, and morning-evening systolic BP between those with and without diabetes.